EFFECT OF HUMAN ERYTHROPOIETIN DERIVED FROM RECOMBINANT DNA ON THE ANAEMIA OF PATIENTS MAINTAINED BY CHRONIC HAEMODIALYSIS

Ten patients with end-stage renal failure and anaemia (mean haemoglobin 6·1 g/dl, range 4·6-8·8 g/dl) on thrice-weekly haemodialysis were treated with human erythropoietin derived from recombinant DNA (rHuEPO). This was given as an intravenous bolus after each dialysis in rising doses within the ran...

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Veröffentlicht in:	The Lancet (British edition) 1986-11, Vol.328 (8517), p.1175-1178
Hauptverfasser:	Winearls, ChristopherG, Pippard, MartinJ, Downing, MichaelR, Oliver, DesmondO, Reid, Cecil, Mary Cotes, P
Format:	Artikel
Sprache:	eng
Schlagworte:	Anemia Clotting Deoxyribonucleic acid Dialysis DNA Drug delivery systems Encephalopathy End-stage renal disease Erythropoietin Hematocrit Hemodialysis Hemoglobin Intravenous administration Kidney diseases Patients Recombinant DNA Renal failure Transfusion
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