RENAL AUTOTRANSPLANTATION FOR SEVERE LOIN-PAIN/HAEMATURIA SYNDROME
Most forms of therapy for the loin-pain/ haematuria syndrome are unsuccessful, though nerve-block procedures and renal denervation sometimes provide temporary relief. Three young patients, with pain so severe that they were dependent on narcotics, were treated for this syndrome. All three had been r...
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| Veröffentlicht in: | The Lancet (British edition) 1985-11, Vol.326 (8466), p.1216-1217 |
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| container_issue | 8466 |
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| container_title | The Lancet (British edition) |
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| creator | Sheil, A.G.R. Thomas, M.A.B. Ibels, L.S. Graham, J.C. |
| description | Most forms of therapy for the loin-pain/ haematuria syndrome are unsuccessful, though nerve-block procedures and renal denervation sometimes provide temporary relief. Three young patients, with pain so severe that they were dependent on narcotics, were treated for this syndrome. All three had been repeatedly admitted to hospital. Loin pain was unilateral in two patients and predominantly so in the third. Renal function, excretion urography, and angiography were normal, but renal biopsy specimens showed deposition of the third component of complement in the renal arterioles. All were treated with renal autotransplantation; the kidney causing pain (or the one causing the most pain) was completely excised and reimplanted in the iliac fossa. Two patients had complete relief of pain and the third almost complete relief, despite recurrence of haematuria in all three. It is too early to determine whether this major procedure is justified in the treatment of the loin-pain/haematuria syndrome, but the early results are encouraging. |
| doi_str_mv | 10.1016/S0140-6736(85)90744-5 |
| format | Article |
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Three young patients, with pain so severe that they were dependent on narcotics, were treated for this syndrome. All three had been repeatedly admitted to hospital. Loin pain was unilateral in two patients and predominantly so in the third. Renal function, excretion urography, and angiography were normal, but renal biopsy specimens showed deposition of the third component of complement in the renal arterioles. All were treated with renal autotransplantation; the kidney causing pain (or the one causing the most pain) was completely excised and reimplanted in the iliac fossa. Two patients had complete relief of pain and the third almost complete relief, despite recurrence of haematuria in all three. It is too early to determine whether this major procedure is justified in the treatment of the loin-pain/haematuria syndrome, but the early results are encouraging.</description><identifier>ISSN: 0140-6736</identifier><identifier>EISSN: 1474-547X</identifier><identifier>DOI: 10.1016/S0140-6736(85)90744-5</identifier><identifier>CODEN: LANCAO</identifier><language>eng</language><publisher>London: Elsevier Ltd</publisher><subject>Angiography ; Arterioles ; Biological and medical sciences ; Biopsy ; Denervation ; Excretion ; Hematuria ; Medical sciences ; Narcotics ; Pain ; Patients ; Renal function ; Surgery (general aspects). Transplantations, organ and tissue grafts. 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Three young patients, with pain so severe that they were dependent on narcotics, were treated for this syndrome. All three had been repeatedly admitted to hospital. Loin pain was unilateral in two patients and predominantly so in the third. Renal function, excretion urography, and angiography were normal, but renal biopsy specimens showed deposition of the third component of complement in the renal arterioles. All were treated with renal autotransplantation; the kidney causing pain (or the one causing the most pain) was completely excised and reimplanted in the iliac fossa. Two patients had complete relief of pain and the third almost complete relief, despite recurrence of haematuria in all three. It is too early to determine whether this major procedure is justified in the treatment of the loin-pain/haematuria syndrome, but the early results are encouraging.</description><subject>Angiography</subject><subject>Arterioles</subject><subject>Biological and medical sciences</subject><subject>Biopsy</subject><subject>Denervation</subject><subject>Excretion</subject><subject>Hematuria</subject><subject>Medical sciences</subject><subject>Narcotics</subject><subject>Pain</subject><subject>Patients</subject><subject>Renal function</subject><subject>Surgery (general aspects). Transplantations, organ and tissue grafts. 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Three young patients, with pain so severe that they were dependent on narcotics, were treated for this syndrome. All three had been repeatedly admitted to hospital. Loin pain was unilateral in two patients and predominantly so in the third. Renal function, excretion urography, and angiography were normal, but renal biopsy specimens showed deposition of the third component of complement in the renal arterioles. All were treated with renal autotransplantation; the kidney causing pain (or the one causing the most pain) was completely excised and reimplanted in the iliac fossa. Two patients had complete relief of pain and the third almost complete relief, despite recurrence of haematuria in all three. It is too early to determine whether this major procedure is justified in the treatment of the loin-pain/haematuria syndrome, but the early results are encouraging.</abstract><cop>London</cop><pub>Elsevier Ltd</pub><doi>10.1016/S0140-6736(85)90744-5</doi><tpages>2</tpages></addata></record> |
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| ispartof | The Lancet (British edition), 1985-11, Vol.326 (8466), p.1216-1217 |
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| source | Elsevier ScienceDirect Journals Complete |
| subjects | Angiography Arterioles Biological and medical sciences Biopsy Denervation Excretion Hematuria Medical sciences Narcotics Pain Patients Renal function Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Surgery of the urinary system Urography |
| title | RENAL AUTOTRANSPLANTATION FOR SEVERE LOIN-PAIN/HAEMATURIA SYNDROME |
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