PI 3K‐ AKT ‐ FOXO 1 pathway targeted by skeletal muscle micro RNA to suppress proteolytic gene expression in response to carbohydrate intake during aerobic exercise

Ingesting protein and carbohydrate together during aerobic exercise suppresses the expression of specific skeletal muscle microRNA and promotes muscle hypertrophy. Determining whether there are independent effects of carbohydrate and protein on microRNA will allow for a clearer understanding of the...

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Veröffentlicht in:	Physiological reports 2018-12, Vol.6 (23), p.e13931
Hauptverfasser:	Margolis, Lee M., Berryman, Claire E., Murphy, Nancy E., Carrigan, Christopher T., Young, Andrew J., Carbone, John W., Pasiakos, Stefan M.
Format:	Artikel
Sprache:	eng
Schlagworte:	1-Phosphatidylinositol 3-kinase Adaptations Aerobics AKT protein Beverages Bioinformatics Carbohydrates Exercise Forkhead protein FOXO1 protein Gene expression Hypertrophy MicroRNAs miRNA Musculoskeletal system Physical fitness Proteasomes Proteins Proteolysis PTEN protein Skeletal muscle Ubiquitin Western blotting Whey protein
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