The Combination of IFN-[alpha]2 and IFN-[alpha]8 Exhibits Synergistic Antiproliferative Activity on Renal Cell Carcinoma (RCC) Cell Lines Through Increased Binding Affinity for IFNAR-2

Although there are at least 13 interferon-alpha (IFN-alpha) subtypes in humans, interactions between the subtypes remain unknown. To understand IFN-alpha interactions, we examined the antiproliferative activities and the receptor binding affinities of different combinations of IFN-alpha2 and IFN-alp...

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Veröffentlicht in:	Journal of interferon & cytokine research 2007-06, Vol.27 (6), p.517
Hauptverfasser:	Tanimoto, Tadao, Yamamoto, Shigeto, Taniai, Madoka, Taniguchi, Mutsuko, Ariyasu, Harumi, Ushio, Chie, Aga, Miho, Mukai, Yohei, Tsutsumi, Yasuo, Ariyasu, Toshio, Ohta, Tsunetaka, Fukuda, Shigeharu
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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