Adenosine test in the diagnosis of unexplained syncope : marker of conducting tissue disease or neurally mediated syncope?
Adenosine test (supine administration of a 20 mg intravenous bolus with electrocardiographic and blood pressure monitoring) has been endorsed by the European Society of Cardiology guidelines on syncope management as an 'experimental' test in the diagnosis of unexplained syncope. The test i...
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| Veröffentlicht in: | European heart journal 2006-06, Vol.27 (12), p.1396-1400 |
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| container_issue | 12 |
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| container_title | European heart journal |
| container_volume | 27 |
| creator | PARRY, Steve W NATH, Samiran BOURKE, John P BEXTON, Rodney S KENNY, Rose Anne |
| description | Adenosine test (supine administration of a 20 mg intravenous bolus with electrocardiographic and blood pressure monitoring) has been endorsed by the European Society of Cardiology guidelines on syncope management as an 'experimental' test in the diagnosis of unexplained syncope. The test is quick and cheap, but there is no consensus as to what condition, if any, the adenosine test is exposing, with conducting tissue disease and neurally mediated syncope proposed by various authors. In this article, we review the possible mechanisms underlying a positive adenosine test, its safety, and a comprehensive examination of the literature supporting each of the putative causal diagnoses. |
| doi_str_mv | 10.1093/eurheartj/ehi844 |
| format | Article |
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The test is quick and cheap, but there is no consensus as to what condition, if any, the adenosine test is exposing, with conducting tissue disease and neurally mediated syncope proposed by various authors. In this article, we review the possible mechanisms underlying a positive adenosine test, its safety, and a comprehensive examination of the literature supporting each of the putative causal diagnoses.</description><identifier>ISSN: 0195-668X</identifier><identifier>EISSN: 1522-9645</identifier><identifier>DOI: 10.1093/eurheartj/ehi844</identifier><identifier>PMID: 16574690</identifier><language>eng</language><publisher>Oxford: Oxford University Press</publisher><subject>Adenosine - adverse effects ; Adenosine Triphosphate - adverse effects ; Biological and medical sciences ; Biomarkers ; Cardiac dysrhythmias ; Cardiology. Vascular system ; Disorders of higher nervous function. Focal brain diseases. Central vestibular syndrome and deafness. Brain stem syndromes ; Drug Interactions ; Headache. Facial pains. Syncopes. Epilepsia. Intracranial hypertension. Brain oedema. 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The test is quick and cheap, but there is no consensus as to what condition, if any, the adenosine test is exposing, with conducting tissue disease and neurally mediated syncope proposed by various authors. In this article, we review the possible mechanisms underlying a positive adenosine test, its safety, and a comprehensive examination of the literature supporting each of the putative causal diagnoses.</description><subject>Adenosine - adverse effects</subject><subject>Adenosine Triphosphate - adverse effects</subject><subject>Biological and medical sciences</subject><subject>Biomarkers</subject><subject>Cardiac dysrhythmias</subject><subject>Cardiology. Vascular system</subject><subject>Disorders of higher nervous function. Focal brain diseases. Central vestibular syndrome and deafness. Brain stem syndromes</subject><subject>Drug Interactions</subject><subject>Headache. Facial pains. Syncopes. Epilepsia. Intracranial hypertension. Brain oedema. Cerebral palsy</subject><subject>Heart</subject><subject>Heart Block - diagnosis</subject><subject>Humans</subject><subject>Medical sciences</subject><subject>Nervous system (semeiology, syndromes)</subject><subject>Neurology</subject><subject>Sick Sinus Syndrome - diagnosis</subject><subject>Syncope - etiology</subject><subject>Vasodilator Agents - adverse effects</subject><issn>0195-668X</issn><issn>1522-9645</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2006</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkN1LwzAUxYMobk7ffZIg-FiXNB9tfZEx_IKBLwq-lTS53TprWpMWnH-9KSvuKXDzO-fecxC6pOSWkozNoXcbUK7bzmFTpZwfoSkVcRxlkotjNCU0E5GU6ccEnXm_JYSkkspTNKFSJFxmZIp-FwZs4ysLuAPf4cribgPYVGo9jD1uStxb-GlrFRiD_c7qpgV8h7-U-wQ3_OvGml53lV3jrvK-H-QelAfcOGzDjaqud_gLgml3sLg_Ryelqj1cjO8MvT8-vC2fo9Xr08tysYo0j2kXcVUaxWQBSsapFEZQMKpgIslKVkBqDCExSxVNTCZ1URZGG8a4yTRQxgknbIau976ta777EDLfNr2zYWUeUyEI5YkIENlD2jXeOyjz1lUh4i6nJB-6zv-7zvddB8nV6NsXIdxBMJYbgJsRUF6runTK6sofuCQVGWeM_QGE2o3G</recordid><startdate>20060601</startdate><enddate>20060601</enddate><creator>PARRY, Steve W</creator><creator>NATH, Samiran</creator><creator>BOURKE, John P</creator><creator>BEXTON, Rodney S</creator><creator>KENNY, Rose Anne</creator><general>Oxford University Press</general><general>Oxford Publishing Limited (England)</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QP</scope><scope>K9.</scope></search><sort><creationdate>20060601</creationdate><title>Adenosine test in the diagnosis of unexplained syncope : marker of conducting tissue disease or neurally mediated syncope?</title><author>PARRY, Steve W ; NATH, Samiran ; BOURKE, John P ; BEXTON, Rodney S ; KENNY, Rose Anne</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c421t-4afda36bea62865d51edab3579f3be8dd00238a17d96cbfbdcd334d9ce1340403</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2006</creationdate><topic>Adenosine - adverse effects</topic><topic>Adenosine Triphosphate - adverse effects</topic><topic>Biological and medical sciences</topic><topic>Biomarkers</topic><topic>Cardiac dysrhythmias</topic><topic>Cardiology. Vascular system</topic><topic>Disorders of higher nervous function. Focal brain diseases. Central vestibular syndrome and deafness. Brain stem syndromes</topic><topic>Drug Interactions</topic><topic>Headache. Facial pains. Syncopes. Epilepsia. Intracranial hypertension. Brain oedema. Cerebral palsy</topic><topic>Heart</topic><topic>Heart Block - diagnosis</topic><topic>Humans</topic><topic>Medical sciences</topic><topic>Nervous system (semeiology, syndromes)</topic><topic>Neurology</topic><topic>Sick Sinus Syndrome - diagnosis</topic><topic>Syncope - etiology</topic><topic>Vasodilator Agents - adverse effects</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>PARRY, Steve W</creatorcontrib><creatorcontrib>NATH, Samiran</creatorcontrib><creatorcontrib>BOURKE, John P</creatorcontrib><creatorcontrib>BEXTON, Rodney S</creatorcontrib><creatorcontrib>KENNY, Rose Anne</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><jtitle>European heart journal</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>PARRY, Steve W</au><au>NATH, Samiran</au><au>BOURKE, John P</au><au>BEXTON, Rodney S</au><au>KENNY, Rose Anne</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Adenosine test in the diagnosis of unexplained syncope : marker of conducting tissue disease or neurally mediated syncope?</atitle><jtitle>European heart journal</jtitle><addtitle>Eur Heart J</addtitle><date>2006-06-01</date><risdate>2006</risdate><volume>27</volume><issue>12</issue><spage>1396</spage><epage>1400</epage><pages>1396-1400</pages><issn>0195-668X</issn><eissn>1522-9645</eissn><abstract>Adenosine test (supine administration of a 20 mg intravenous bolus with electrocardiographic and blood pressure monitoring) has been endorsed by the European Society of Cardiology guidelines on syncope management as an 'experimental' test in the diagnosis of unexplained syncope. The test is quick and cheap, but there is no consensus as to what condition, if any, the adenosine test is exposing, with conducting tissue disease and neurally mediated syncope proposed by various authors. In this article, we review the possible mechanisms underlying a positive adenosine test, its safety, and a comprehensive examination of the literature supporting each of the putative causal diagnoses.</abstract><cop>Oxford</cop><pub>Oxford University Press</pub><pmid>16574690</pmid><doi>10.1093/eurheartj/ehi844</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
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| ispartof | European heart journal, 2006-06, Vol.27 (12), p.1396-1400 |
| issn | 0195-668X 1522-9645 |
| language | eng |
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| source | MEDLINE; Oxford University Press Journals All Titles (1996-Current); EZB-FREE-00999 freely available EZB journals |
| subjects | Adenosine - adverse effects Adenosine Triphosphate - adverse effects Biological and medical sciences Biomarkers Cardiac dysrhythmias Cardiology. Vascular system Disorders of higher nervous function. Focal brain diseases. Central vestibular syndrome and deafness. Brain stem syndromes Drug Interactions Headache. Facial pains. Syncopes. Epilepsia. Intracranial hypertension. Brain oedema. Cerebral palsy Heart Heart Block - diagnosis Humans Medical sciences Nervous system (semeiology, syndromes) Neurology Sick Sinus Syndrome - diagnosis Syncope - etiology Vasodilator Agents - adverse effects |
| title | Adenosine test in the diagnosis of unexplained syncope : marker of conducting tissue disease or neurally mediated syncope? |
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