Multichannel PDMS microfluidic based nano-biolab-on-a-chip for medical diagnostics
Lab-on-a-chip (LOC) is becoming a dominant tool for point-of-care (POC) diagnostics in the medical field, in the recent years. Multi-disease analysis using single chip via delivery of fluid with the same condition of multiple transducers without contamination is the pathway of multi-channel microflu...
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| creator | Rajapaksha, R. D. A. A. Azman, N. A. N. Uda, M. N. Afnan Hashim, U. Gopinath, S. C. B. Fernando, C. A. N. |
| description | Lab-on-a-chip (LOC) is becoming a dominant tool for point-of-care (POC) diagnostics in the medical field, in the recent years. Multi-disease analysis using single chip via delivery of fluid with the same condition of multiple transducers without contamination is the pathway of multi-channel microfluidic based LOCs. The LOC system was designed using SOLTDWORKS software. The microfluidic photomask was designed by using AutoCAD software to make chrome mask. The SU-8 negative photoresist was used for master mold preparation through a photolithography process. PDMS was used as a medium of the microfluidic. The low power microscope, high power microscope, and surface profilometer were used to morphologically characterize the microfluidic mold and the PDMS microfluidic. 3-in-l nano biosensor kit was attached with the microfluidic to produce Nano-Biolab-on-a-chip (NBLOC) device. The structural integrity of the system was observed by dropping food coloring dye through the inlet and collecting at the outlet. |
| doi_str_mv | 10.1063/1.5080833 |
| format | Conference Proceeding |
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D. A. A. ; Azman, N. A. N. ; Uda, M. N. Afnan ; Hashim, U. ; Gopinath, S. C. B. ; Fernando, C. A. N.</creator><contributor>Ismail, Nur Syakimah ; Ramli, Muhammad Mahyiddin ; Wei-Wen, Liu ; Hong, Voon Chun ; Isa, Siti Salwa Mat ; Fathil, Mohamad Faris Mohamad</contributor><creatorcontrib>Rajapaksha, R. D. A. A. ; Azman, N. A. N. ; Uda, M. N. Afnan ; Hashim, U. ; Gopinath, S. C. B. ; Fernando, C. A. N. ; Ismail, Nur Syakimah ; Ramli, Muhammad Mahyiddin ; Wei-Wen, Liu ; Hong, Voon Chun ; Isa, Siti Salwa Mat ; Fathil, Mohamad Faris Mohamad</creatorcontrib><description>Lab-on-a-chip (LOC) is becoming a dominant tool for point-of-care (POC) diagnostics in the medical field, in the recent years. Multi-disease analysis using single chip via delivery of fluid with the same condition of multiple transducers without contamination is the pathway of multi-channel microfluidic based LOCs. The LOC system was designed using SOLTDWORKS software. The microfluidic photomask was designed by using AutoCAD software to make chrome mask. The SU-8 negative photoresist was used for master mold preparation through a photolithography process. PDMS was used as a medium of the microfluidic. The low power microscope, high power microscope, and surface profilometer were used to morphologically characterize the microfluidic mold and the PDMS microfluidic. 3-in-l nano biosensor kit was attached with the microfluidic to produce Nano-Biolab-on-a-chip (NBLOC) device. 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The low power microscope, high power microscope, and surface profilometer were used to morphologically characterize the microfluidic mold and the PDMS microfluidic. 3-in-l nano biosensor kit was attached with the microfluidic to produce Nano-Biolab-on-a-chip (NBLOC) device. The structural integrity of the system was observed by dropping food coloring dye through the inlet and collecting at the outlet.</description><subject>Biosensors</subject><subject>CAD</subject><subject>Coloring</subject><subject>Computer aided design</subject><subject>Microfluidics</subject><subject>Photolithography</subject><subject>Photoresists</subject><subject>Polydimethylsiloxane</subject><subject>Silicone resins</subject><subject>Software</subject><subject>Structural integrity</subject><subject>Transducers</subject><issn>0094-243X</issn><issn>1551-7616</issn><fulltext>true</fulltext><rsrctype>conference_proceeding</rsrctype><creationdate>2018</creationdate><recordtype>conference_proceeding</recordtype><recordid>eNotkE1LwzAch4MoOKcHv0HAm5D5T5O06VHmK2wovoC3kKSJy-iS2rQHv72V7fS7PDw_eBC6pLCgULIbuhAgQTJ2hGZUCEqqkpbHaAZQc1Jw9nWKznLeAhR1VckZeluP7RDsRsfoWvx6t37Hu2D75NsxNMFio7NrcNQxERNSqw1JkWhiN6HDPvV45yZKt7gJ-jumPKnyOTrxus3u4rBz9Plw_7F8IquXx-fl7YrYQsiBcKaNKbyXnpsGhPbAaMVM6b0wVAtuwQnprJF1za2BArSgkkPlAZqmpp7N0dXe2_XpZ3R5UNs09nG6VAWdKpRQcZio6z2VbRj0EFJUXR92uv9VFNR_M0XVoRn7Ax3TXfM</recordid><startdate>20181206</startdate><enddate>20181206</enddate><creator>Rajapaksha, R. 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N.</au><au>Ismail, Nur Syakimah</au><au>Ramli, Muhammad Mahyiddin</au><au>Wei-Wen, Liu</au><au>Hong, Voon Chun</au><au>Isa, Siti Salwa Mat</au><au>Fathil, Mohamad Faris Mohamad</au><format>book</format><genre>proceeding</genre><ristype>CONF</ristype><atitle>Multichannel PDMS microfluidic based nano-biolab-on-a-chip for medical diagnostics</atitle><btitle>AIP conference proceedings</btitle><date>2018-12-06</date><risdate>2018</risdate><volume>2045</volume><issue>1</issue><issn>0094-243X</issn><eissn>1551-7616</eissn><coden>APCPCS</coden><abstract>Lab-on-a-chip (LOC) is becoming a dominant tool for point-of-care (POC) diagnostics in the medical field, in the recent years. Multi-disease analysis using single chip via delivery of fluid with the same condition of multiple transducers without contamination is the pathway of multi-channel microfluidic based LOCs. The LOC system was designed using SOLTDWORKS software. The microfluidic photomask was designed by using AutoCAD software to make chrome mask. The SU-8 negative photoresist was used for master mold preparation through a photolithography process. PDMS was used as a medium of the microfluidic. The low power microscope, high power microscope, and surface profilometer were used to morphologically characterize the microfluidic mold and the PDMS microfluidic. 3-in-l nano biosensor kit was attached with the microfluidic to produce Nano-Biolab-on-a-chip (NBLOC) device. The structural integrity of the system was observed by dropping food coloring dye through the inlet and collecting at the outlet.</abstract><cop>Melville</cop><pub>American Institute of Physics</pub><doi>10.1063/1.5080833</doi><tpages>7</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0094-243X |
| ispartof | AIP conference proceedings, 2018, Vol.2045 (1) |
| issn | 0094-243X 1551-7616 |
| language | eng |
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| source | AIP Journals Complete |
| subjects | Biosensors CAD Coloring Computer aided design Microfluidics Photolithography Photoresists Polydimethylsiloxane Silicone resins Software Structural integrity Transducers |
| title | Multichannel PDMS microfluidic based nano-biolab-on-a-chip for medical diagnostics |
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