Oncolytic cancer therapy with a vaccinia virus strain

Oncolytic vaccinia virus is currently undergoing evaluation as a biological anticancer agent in clinical trials. This treatment exploits the lytic nature of a viral infection to eradicate the tumor mass in a cancer cell‑specific manner. So far, various vaccinia strains have been used as backbones in...

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Bibliographische Detailangaben
Veröffentlicht in:	Oncology reports 2019-01, Vol.41 (1), p.686-692
Hauptverfasser:	Deng, Lili, Fan, Jun, Ding, Yuedi, Zhang, Jue, Zhou, Bin, Zhang, Yi, Huang, Biao, Hu, Zhigang
Format:	Artikel
Sprache:	eng
Schlagworte:	A549 Cells Animals Cancer research Cancer therapies Care and treatment Cell Line Cell Line, Tumor Cytotoxicity Development and progression Female HeLa Cells Humans Immunotherapy Laboratory animals Male Melanoma Methods Mice Mice, Inbred C57BL Middle Aged Neoplasms - therapy Neoplasms - virology NIH 3T3 Cells Oncolytic viral therapy Oncolytic Virotherapy - methods Oncolytic Viruses - physiology Patient outcomes Studies Tissue Distribution - physiology Tumors Vaccines Vaccinia Vaccinia virus - physiology Virus Replication - physiology Viruses Xenograft Model Antitumor Assays - methods
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