Naringenin enhances insulin-stimulated tyrosine phosphorylation and improves the cellular actions of insulin in a dietary model of metabolic syndrome

Background There is a growing interest in identifying putative insulin sensitizers from the herbal sources. Aim of the study The present study explores the effects of naringenin, a bioflavonoid, in the high fructose-induced model of insulin resistance. Methods Adult male Wistar rats were divided int...

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Veröffentlicht in:	European journal of nutrition 2010-03, Vol.49 (2), p.101-109
Hauptverfasser:	Kannappan, Sriramajayam, Anuradha, Carani Venkatraman
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Chemistry Chemistry and Materials Science Diabetes Mellitus, Experimental - metabolism Diabetes Mellitus, Experimental - pathology Diabetes Mellitus, Experimental - prevention & control Diet - adverse effects Flavanones - pharmacology Fructose - toxicity Glycogen - metabolism Hypoglycemic Agents - pharmacology Insulin - blood Insulin - pharmacology Liver - drug effects Liver - metabolism Liver - pathology Male Metabolic Syndrome - chemically induced Metabolic Syndrome - metabolism Metabolic Syndrome - pathology Metabolic Syndrome - prevention & control Muscle, Skeletal - drug effects Muscle, Skeletal - enzymology Muscle, Skeletal - metabolism Nutrition Original Contribution Phosphorylation Phytotherapy Protein Processing, Post-Translational - drug effects Protein Tyrosine Phosphatases - metabolism Protein-Tyrosine Kinases - metabolism Rats Rats, Wistar Tyrosine - metabolism
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