Biodistribution and radiation dosimetry of [11C]raclopride in healthy volunteers

This study reports on the whole-body biodistribution and radiation dosimetry of [11C]raclopride, a dopamine D2 receptor antagonist. In three healthy male volunteers, whole-body scans were performed up to 2 h following i.v. injection of 320+/-65 MBq [11C]raclopride. Transmission scans (3 min per step...

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Veröffentlicht in:	European journal of nuclear medicine and molecular imaging 2005-08, Vol.32 (8), p.952-958
Hauptverfasser:	Ribeiro, Maria-João, Ricard, Marcel, Bourgeois, Sandrine, Lièvre, Marie-Angele, Bottlaender, Michel, Gervais, Philippe, Dollé, Frédéric, Syrota, André
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Body Burden Brain - diagnostic imaging Brain - metabolism Humans Injections, Intravenous Male Metabolic Clearance Rate Organ Specificity Raclopride - pharmacokinetics Radiation Dosage Radionuclide Imaging Radiopharmaceuticals - administration & dosage Radiopharmaceuticals - pharmacokinetics Reference Values Tissue Distribution Whole-Body Counting
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