PET imaging of apoptosis with 64Cu-labeled streptavidin following pretargeting of phosphatidylserine with biotinylated annexin-V

Purpose In vivo detection of apoptosis is a diagnostic tool with potential clinical applications in cardiology and oncology. Radiolabeled annexin-V (anxV) is an ideal probe for in vivo apoptosis detection owing to its strong affinity for phosphatidylserine (PS), the molecular flag on the surface of...

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Veröffentlicht in:	European journal of nuclear medicine and molecular imaging 2007-02, Vol.34 (2), p.247-258
Hauptverfasser:	Cauchon, Nicole, Langlois, Réjean, Rousseau, Jacques A., Tessier, Guillaume, Cadorette, Jules, Lecomte, Roger, Hunting, Darel J., Pavan, Roberto A., Zeisler, Stefan K., van Lier, Johan E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Medical diagnosis Medical imaging Oncology
Online-Zugang:	Volltext
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