Prevention of acetic acid-induced colitis by desferrithiocin analogs in a rat model

Iron contributes significantly to the formation of reactive oxygen species via the Fenton reaction. Therefore, we assessed whether a series of desferrithiocin analogs, both carboxylic acids and hydroxamates, could (1) either promote or diminish the iron-mediated oxidation of ascorbate, (2) quench a...

Ausführliche Beschreibung