Intestinal Ischemia in Systemic Lupus Erythematosus
Bowel ischemia, an uncommon but devastating complication of systemic lupus erythematosus (SLE), poses a significant clinical challenge. A 52-year-old female with SLE presented with recurrent abdominal pain for two months which culminated in acute, severe pain with vomiting. Abdominal CT scan reveale...
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| Veröffentlicht in: | Journal of the National Medical Association 2008-06, Vol.100 (6), p.721-723 |
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| creator | Lee, Michael G., MD Hagley, Karlene, MD Decuaelar, Karel, MD |
| description | Bowel ischemia, an uncommon but devastating complication of systemic lupus erythematosus (SLE), poses a significant clinical challenge. A 52-year-old female with SLE presented with recurrent abdominal pain for two months which culminated in acute, severe pain with vomiting. Abdominal CT scan revealed ischemia of multiple segments of bowel. She responded slowly to methylprednisolone alone and eventually responded to methylprednisolone combined with cyclophosphamide. A high index of suspicion for bowel ischemia is required in patients with SLE presenting with acute abdominal pain. |
| doi_str_mv | 10.1016/S0027-9684(15)31349-3 |
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A 52-year-old female with SLE presented with recurrent abdominal pain for two months which culminated in acute, severe pain with vomiting. Abdominal CT scan revealed ischemia of multiple segments of bowel. She responded slowly to methylprednisolone alone and eventually responded to methylprednisolone combined with cyclophosphamide. A high index of suspicion for bowel ischemia is required in patients with SLE presenting with acute abdominal pain.</description><identifier>ISSN: 0027-9684</identifier><identifier>EISSN: 1943-4693</identifier><identifier>DOI: 10.1016/S0027-9684(15)31349-3</identifier><identifier>PMID: 18595576</identifier><identifier>CODEN: JNMAAE</identifier><language>eng</language><publisher>Thorofare, NJ: Elsevier Inc</publisher><subject>Abdomen, Acute - drug therapy ; Abdomen, Acute - etiology ; Biological and medical sciences ; Cyclophosphamide - administration & dosage ; Drug Therapy, Combination ; Female ; Gastroenterology. Liver. Pancreas. Abdomen ; General aspects ; Humans ; Internal Medicine ; Intestines - blood supply ; Ischemia - diagnostic imaging ; Ischemia - drug therapy ; Ischemia - etiology ; lupus abdomen pain ; Lupus Erythematosus, Systemic - complications ; Medical sciences ; Mesenteric Arteries ; Methylprednisolone - administration & dosage ; Middle Aged ; Other diseases. Semiology ; Stomach. Duodenum. Small intestine. Colon. Rectum. 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A 52-year-old female with SLE presented with recurrent abdominal pain for two months which culminated in acute, severe pain with vomiting. Abdominal CT scan revealed ischemia of multiple segments of bowel. She responded slowly to methylprednisolone alone and eventually responded to methylprednisolone combined with cyclophosphamide. A high index of suspicion for bowel ischemia is required in patients with SLE presenting with acute abdominal pain.</description><subject>Abdomen, Acute - drug therapy</subject><subject>Abdomen, Acute - etiology</subject><subject>Biological and medical sciences</subject><subject>Cyclophosphamide - administration & dosage</subject><subject>Drug Therapy, Combination</subject><subject>Female</subject><subject>Gastroenterology. Liver. Pancreas. Abdomen</subject><subject>General aspects</subject><subject>Humans</subject><subject>Internal Medicine</subject><subject>Intestines - blood supply</subject><subject>Ischemia - diagnostic imaging</subject><subject>Ischemia - drug therapy</subject><subject>Ischemia - etiology</subject><subject>lupus abdomen pain</subject><subject>Lupus Erythematosus, Systemic - complications</subject><subject>Medical sciences</subject><subject>Mesenteric Arteries</subject><subject>Methylprednisolone - administration & dosage</subject><subject>Middle Aged</subject><subject>Other diseases. Semiology</subject><subject>Stomach. Duodenum. Small intestine. Colon. Rectum. 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Liver. Pancreas. Abdomen</topic><topic>General aspects</topic><topic>Humans</topic><topic>Internal Medicine</topic><topic>Intestines - blood supply</topic><topic>Ischemia - diagnostic imaging</topic><topic>Ischemia - drug therapy</topic><topic>Ischemia - etiology</topic><topic>lupus abdomen pain</topic><topic>Lupus Erythematosus, Systemic - complications</topic><topic>Medical sciences</topic><topic>Mesenteric Arteries</topic><topic>Methylprednisolone - administration & dosage</topic><topic>Middle Aged</topic><topic>Other diseases. Semiology</topic><topic>Stomach. Duodenum. Small intestine. Colon. Rectum. 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A 52-year-old female with SLE presented with recurrent abdominal pain for two months which culminated in acute, severe pain with vomiting. Abdominal CT scan revealed ischemia of multiple segments of bowel. She responded slowly to methylprednisolone alone and eventually responded to methylprednisolone combined with cyclophosphamide. A high index of suspicion for bowel ischemia is required in patients with SLE presenting with acute abdominal pain.</abstract><cop>Thorofare, NJ</cop><pub>Elsevier Inc</pub><pmid>18595576</pmid><doi>10.1016/S0027-9684(15)31349-3</doi><tpages>3</tpages></addata></record> |
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| subjects | Abdomen, Acute - drug therapy Abdomen, Acute - etiology Biological and medical sciences Cyclophosphamide - administration & dosage Drug Therapy, Combination Female Gastroenterology. Liver. Pancreas. Abdomen General aspects Humans Internal Medicine Intestines - blood supply Ischemia - diagnostic imaging Ischemia - drug therapy Ischemia - etiology lupus abdomen pain Lupus Erythematosus, Systemic - complications Medical sciences Mesenteric Arteries Methylprednisolone - administration & dosage Middle Aged Other diseases. Semiology Stomach. Duodenum. Small intestine. Colon. Rectum. Anus Tomography, X-Ray Computed Treatment Outcome |
| title | Intestinal Ischemia in Systemic Lupus Erythematosus |
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