Minor Increases in Plasma Troponin I Predict Decreased Left Ventricular Ejection Fraction after High-Dose Chemotherapy

Increased cardiac troponin I (cTnI) in patients treated with high-dose chemotherapy (HDCT) for aggressive malignancy has been proposed as an early marker of late HDCT-induced cardiac dysfunction. We investigated whether cTnI measured by the Stratus CS (Dade Behring) would allow detection of minimal...

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Veröffentlicht in:	Clinical chemistry (Baltimore, Md.) Md.), 2003-02, Vol.49 (2), p.248-252
Hauptverfasser:	Sandri, Maria Teresa, Cardinale, Daniela, Zorzino, Laura, Passerini, Rita, Lentati, Paola, Martinoni, Alessandro, Martinelli, Giovanni, Cipolla, Carlo Maria
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic Agents - administration & dosage Antineoplastic Agents - adverse effects Biological and medical sciences Cardiac function Cardiovascular disease Cardiovascular system Chemotherapy Dose-Response Relationship, Drug Drug dosages Ejection fraction Female Heart attacks Humans Investigative techniques, diagnostic techniques (general aspects) Kinases Male Medical sciences Middle Aged Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques Patients Prospective Studies Stroke Volume - drug effects Troponin I - blood Ultrasonic imaging Ultrasonography Ventricular Dysfunction, Left - chemically induced Ventricular Dysfunction, Left - diagnostic imaging Ventricular Dysfunction, Left - physiopathology
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