SMOOTH-MUSCLE ANTIBODIES IN INFERTILITY

Sera from 77 infertile women and 77 post-partum controls were examined for autoantibodies by indirect immunofluorescence. 27 (35%) of the infertile group had smooth-muscle antibody compared with 2 (3%) controls. Significantly more infertile patients had anti-nuclear factor, and reticulin antibodies...

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Veröffentlicht in:	The Lancet (British edition) 1975-12, Vol.306 (7947), p.1238-1239
Hauptverfasser:	Wilson, C, Elstein, Max, Eade, O.E, Lloyd, R, Wright, Ralph
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies Autoantibodies Immunofluorescence Immunoglobulins Infertility Muscles Smooth muscle
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creator	Wilson, C Elstein, Max Eade, O.E Lloyd, R Wright, Ralph
description	Sera from 77 infertile women and 77 post-partum controls were examined for autoantibodies by indirect immunofluorescence. 27 (35%) of the infertile group had smooth-muscle antibody compared with 2 (3%) controls. Significantly more infertile patients had anti-nuclear factor, and reticulin antibodies were also more commonly found in this group. The differences for organ-specific autoantibodies between the two groups were not significant. There was no correlation between the occurrence of smooth-muscle antibodies and immunofluorescent anti-sperm antibodies. The high frequency of smooth-muscle antibodies in infertile women requires further study to determine whether an underlying viral infection is involved.
doi_str_mv	10.1016/S0140-6736(75)92074-7
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The high frequency of smooth-muscle antibodies in infertile women requires further study to determine whether an underlying viral infection is involved.</description><subject>Antibodies</subject><subject>Autoantibodies</subject><subject>Immunofluorescence</subject><subject>Immunoglobulins</subject><subject>Infertility</subject><subject>Muscles</subject><subject>Smooth muscle</subject><issn>0140-6736</issn><issn>1474-547X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1975</creationdate><recordtype>article</recordtype><recordid>eNqFUF1LwzAUDaLgnP4EYeCD-lC9SZve5Enm7FyhW8F2oE-hSxPo0HUmm-C_t9vEV-HCvVzOB-cQcknhjgKN7wugEQQxhvEN8lvJAKMAj0iPRt3BI3w9Jr0_yCk5834JAFEMvEeui2mel5NgOi9GWTIYzsr0MX9Kk2KQzroZJy9lmqXl2zk5sdW7Nxe_u0_m46QcTYIsf05HwyzQIbBNUCFgvMBQ1kJLjQtcCCtiKqm0TNaSVxCykFlgpnsyIajgVlouLGopjTFhn1wddNeu_dwav1HLdutWnaViNJScY4TQofgBpV3rvTNWrV3zUblvRUHtOlH7TtQusEKu9p0o7HgPB57pInw1ximvG7PSpm6c0RtVt80_Cj_BQmLL</recordid><startdate>19751220</startdate><enddate>19751220</enddate><creator>Wilson, C</creator><creator>Elstein, Max</creator><creator>Eade, O.E</creator><creator>Lloyd, R</creator><creator>Wright, Ralph</creator><general>Elsevier Ltd</general><general>Elsevier Limited</general><scope>AAYXX</scope><scope>CITATION</scope><scope>7QL</scope><scope>7QP</scope><scope>7TK</scope><scope>7U7</scope><scope>7U9</scope><scope>ASE</scope><scope>C1K</scope><scope>FPQ</scope><scope>H94</scope><scope>K6X</scope><scope>K9.</scope><scope>KB~</scope><scope>M7N</scope><scope>NAPCQ</scope></search><sort><creationdate>19751220</creationdate><title>SMOOTH-MUSCLE ANTIBODIES IN INFERTILITY</title><author>Wilson, C ; Elstein, Max ; Eade, O.E ; Lloyd, R ; Wright, Ralph</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c302t-a7076b739d8c9c7b7b8f861919f29d95a03232f02e619288185f9f58f7c99eee3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1975</creationdate><topic>Antibodies</topic><topic>Autoantibodies</topic><topic>Immunofluorescence</topic><topic>Immunoglobulins</topic><topic>Infertility</topic><topic>Muscles</topic><topic>Smooth muscle</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Wilson, C</creatorcontrib><creatorcontrib>Elstein, Max</creatorcontrib><creatorcontrib>Eade, O.E</creatorcontrib><creatorcontrib>Lloyd, R</creatorcontrib><creatorcontrib>Wright, Ralph</creatorcontrib><collection>CrossRef</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>Toxicology Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>British Nursing Index</collection><collection>Environmental Sciences and Pollution Management</collection><collection>British Nursing Index (BNI) (1985 to Present)</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>British Nursing Index</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>ProQuest Newsstand Professional</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Nursing & Allied Health Premium</collection><jtitle>The Lancet (British edition)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Wilson, C</au><au>Elstein, Max</au><au>Eade, O.E</au><au>Lloyd, R</au><au>Wright, Ralph</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>SMOOTH-MUSCLE ANTIBODIES IN INFERTILITY</atitle><jtitle>The Lancet (British edition)</jtitle><date>1975-12-20</date><risdate>1975</risdate><volume>306</volume><issue>7947</issue><spage>1238</spage><epage>1239</epage><pages>1238-1239</pages><issn>0140-6736</issn><eissn>1474-547X</eissn><abstract>Sera from 77 infertile women and 77 post-partum controls were examined for autoantibodies by indirect immunofluorescence. 27 (35%) of the infertile group had smooth-muscle antibody compared with 2 (3%) controls. 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subjects	Antibodies Autoantibodies Immunofluorescence Immunoglobulins Infertility Muscles Smooth muscle
title	SMOOTH-MUSCLE ANTIBODIES IN INFERTILITY
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