Amiodarone concentration in human myocardium after rapid intravenous administration

Intravenous amiodarone has been found useful in the emergent management of life-threatening arrhythmias. Experimental studies have shown that its electrophysiologic effects are proportional to its myocardial concentration. However, early after its intravenous administration, the extent of the concen...

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Veröffentlicht in:	Cardiovascular drugs and therapy 1999-05, Vol.13 (3), p.265-270
Hauptverfasser:	ANASTASIOU-NANA, M. I, NANAS, J. N, ALEXOPOULOS, G, KARLI, J. N, MARGARI, Z. J, AGAPITOS, E, PATSI, E. N, STAMATELOPOULOS, S. F
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Amiodarone - administration & dosage Amiodarone - adverse effects Amiodarone - blood Amiodarone - pharmacokinetics Anti-Arrhythmia Agents - administration & dosage Anti-Arrhythmia Agents - adverse effects Anti-Arrhythmia Agents - blood Anti-Arrhythmia Agents - pharmacokinetics Antiarythmic agents Biological and medical sciences Body Weight - physiology Cardiomyopathy, Dilated - metabolism Cardiomyopathy, Dilated - physiopathology Cardiovascular system Female Fibrosis Heart Failure - metabolism Heart Failure - physiopathology Hemodynamics - drug effects Humans Injections, Intravenous Male Medical sciences Middle Aged Myocardium - metabolism Myocardium - pathology Pharmacology. Drug treatments Vasodilator Agents - administration & dosage Vasodilator Agents - adverse effects Vasodilator Agents - blood Vasodilator Agents - pharmacokinetics
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