Nitrative stress and poly(ADP-ribose) polymerase activation in healthy and gestational diabetic pregnancies

Aims/hypothesis Increased oxidative-nitrosative stress, poly(ADP-ribose) polymerase (PARP) activation and subsequent cellular damage play important roles in the complications of both diabetes mellitus and pregnancy. Our aim was to investigate nitrative stress and PARP activity levels during normal a...

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Veröffentlicht in:	Diabetologia 2009-09, Vol.52 (9), p.1935-1943
Hauptverfasser:	Horváth, E. M, Magenheim, R, Kugler, E, Vácz, G, Szigethy, A, Lévárdi, F, Kollai, M, Szabo, C, Lacza, Z
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Apoptosis Biological and medical sciences Birth Weight Blood Glucose - analysis Body Mass Index Carbohydrates Diabetes, Gestational - blood Diabetes, Gestational - drug therapy Diabetes, Gestational - enzymology Diabetes. Impaired glucose tolerance Diet, Diabetic Dietary restrictions Endocrine pancreas. Apud cells (diseases) Endocrinopathies Enzyme Activation Female Gestational diabetes Glucose Glucose Tolerance Test Human Physiology Humans Hypoglycemic Agents - therapeutic use Infant, Newborn Infant, Small for Gestational Age Insulin Insulin - therapeutic use Internal Medicine Leukocytes Leukocytes - cytology Medical sciences Medicine Medicine & Public Health Metabolic Diseases Obstetric Labor, Premature Oxidative stress Parity Physiology Poly(ADP-ribose) Polymerases - metabolism Pregnancy Pregnancy - blood Pregnancy - physiology Reference Values Umbilical cord Weight Gain
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