PO-0050 Absent Pulmonary Valve In A Patient With Alagille Syndrome

Background and aimsAbsent pulmonary valve (APV) is a rare congenital defect of the right ventricular outflow tract (RVOT). The genetics of APV are unknown. However, mutations in the NOTCH-signalling pathway have been associated with RVOT obstruction. Mutations in the JAG-1 gene cause a broad spectru...

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