PS-326 Toll-like Receptor 1(tlr1)gene Snp Rs5743618 Is Associated With Increased Risk For Tuberculosis In Han Chinese Children

Toll-like receptor 1 (TLR1) recognises lipopeptides with TLR2, and affects immune response to Mycobacterium tuberculosis infection. Here, we report results of the first case-control paediatric study of the TLR1 single-nucleotide polymorphisms and susceptibility to tuberculosis (TB). A paediatric cas...

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Veröffentlicht in:	Archives of disease in childhood 2014-10, Vol.99 (Suppl 2), p.A228-A229
Hauptverfasser:	Qi, H, Sun, L, Xu, F, Shen, AD
Format:	Artikel
Sprache:	eng
Schlagworte:	Alleles Children Control Groups CXC chemokines CXCL10 protein Genotypes Immune response Interleukin 12 Lipopeptides Single-nucleotide polymorphism TLR1 protein TLR2 protein Toll-like receptors Tuberculosis Tumor necrosis factor-TNF Tumor necrosis factor-α Tumors
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