New heteroleptic oxidovanadium(V) complexes: synthesis, characterization and biological evaluation as potential agents against Trypanosoma cruzi

Searching for prospective vanadium-based agents against Trypanosoma cruzi , the parasite causing Chagas disease, four new [V V O(8HQ–H)(L–2H)] compounds, where 8HQ is 8-hydroxyquinoline and L are tridentate salicylaldehyde semicarbazone derivatives L1–L4, were synthesized and characterized in the so...

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Veröffentlicht in:	Journal of biological inorganic chemistry 2018-12, Vol.23 (8), p.1265-1281
Hauptverfasser:	Scalese, Gonzalo, Machado, Ignacio, Fontana, Carolina, Risi, Gastón, Salinas, Gustavo, Pérez-Díaz, Leticia, Gambino, Dinorah
Format:	Artikel
Sprache:	eng
Schlagworte:	8-Hydroxyquinoline Apoptosis Biochemistry Biomedical and Life Sciences Cell death Chagas disease Epimastigotes Inorganic chemistry Life Sciences Microbiology Nifurtimox Original Paper Parasites Phenotypes Protozoa Toxicity Trypanosoma cruzi Vanadium Vero cells
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