Comparative p16^sup IKN4A^ Expression in Laryngeal Carcinoma and Cervical Cancer Precursors: A Real-time Grid-based Immunocytochemistry Analysis

Background/Aim: p16 (gene locus: 9p21) tumor suppressor gene is considered an important biomarker for the progression and prognosis in a variety of malignancies and pre-cancerous lesions, including high-risk (HR−) human papilloma virus (HPV)-mediated squamous intraepithelial lesions (SILs), based on...

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Veröffentlicht in:	Anticancer research 2018-10, Vol.38 (10), p.5805
Hauptverfasser:	Tsiambas, Evangelos, Riziotis, Christos, Mastronikolis, Nicholas S, Peschos, Dimitrios, Mortakis, Alexandros, Kyroysis, Grigorios, Mastronikolis, Stylianos N, Batistatou, Anna, Lazaris, Andreas C, Patsouris, Efstratios, Ragos, Vasileios
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomarkers Calibration Cancer Cell cycle Cervical cancer Cervix Classification Cyclin-dependent kinase Cyclin-dependent kinases Deoxyribonucleic acid Diagnostic systems DNA E2F protein Enzyme inhibitors Gene expression Genetic transformation Health risks Human papillomavirus Immunocytochemistry Immunohistochemistry Kinases Laryngeal cancer Laryngeal carcinoma Lesions Overexpression p16 Protein Phenotypes Protein expression Proteins Proteolysis Real time Retina Retinoblastoma Retinoblastoma protein S phase Screening Smoking Squamous cell carcinoma Tissues Transcription Tumor suppressor genes Viruses
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