Kras in Organoids

Oncogenic Kras are genetic dependencies for the majority of pancreatic and colorectal adenocarcinomas; however, much remains to be understood regarding its tropism to these carcinomas. Recently developed organoid technology presents a more representative model culture system for pancreatic and colon...

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Veröffentlicht in:	Cold Spring Harbor perspectives in biology 2018-04, Vol.10 (4)
Hauptverfasser:	Cheng, Derek, Tuveson, David
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal models Cancer Carcinoma Cell culture Colon Gene expression Genetic engineering In vivo methods and tests K-Ras protein Organoids Pancreas Tropism Tumors
Online-Zugang:	Volltext
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