Copper-catalyzed oxidative coupling of quinoxalin-2(1 H )-ones with alcohols: access to hydroxyalkylation of quinoxalin-2(1 H )-ones

An efficient copper-catalyzed protocol for the synthesis of hydroxyl-containing quinoxalin-2(1 H )-ones from the radical reaction of quinoxalin-2(1 H )-ones with alcohols was developed with moderate to good yields. Quinoxalin-2(1 H )-ones were coupled with alkyl radicals through direct catalytic fun...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Organic Chemistry Frontiers 2018-12, Vol.5 (23), p.3382-3390
Hauptverfasser:	Fu, Junhao, Yuan, Jinwei, Zhang, Yue, Xiao, Yongmei, Mao, Pu, Diao, Xiaoqiong, Qu, Lingbo
Format:	Artikel
Sprache:	eng
Schlagworte:	Alcohol Alcohols Atom economy Catalysis Chemical synthesis Copper Functional groups Hydrogen bonds Organic chemistry Substrates
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!