Pharmacological correction of hemostasis-regulating function of the lungs in rats with uncomplicated pregnancy and experimental gestosis

Fetal growth retardation, hypercoagulation, and changes in pulmonary fibrinolytic activity were observed during experimental gestosis induced by long-term feeding of a high-sodium diet. The course of fraxiparine treatment to correct gestosis improved hemostasis-regulating lung function, decreased co...

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Veröffentlicht in:Bulletin of experimental biology and medicine 2005-06, Vol.139 (6), p.651-654
Hauptverfasser: Myasnikova, V V, Galenko-Yaroshevskii, P A, Lysenkov, S P, Gigineishvili, M A, Berberashvili, T M
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container_issue 6
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container_title Bulletin of experimental biology and medicine
container_volume 139
creator Myasnikova, V V
Galenko-Yaroshevskii, P A
Lysenkov, S P
Gigineishvili, M A
Berberashvili, T M
description Fetal growth retardation, hypercoagulation, and changes in pulmonary fibrinolytic activity were observed during experimental gestosis induced by long-term feeding of a high-sodium diet. The course of fraxiparine treatment to correct gestosis improved hemostasis-regulating lung function, decreased coagulation activity of the arterial blood, and increased the weights of the placenta and fetus.
doi_str_mv 10.1007/s10517-005-0368-1
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subjects Animals
Anticoagulants - pharmacology
Birth Weight - drug effects
Blood Coagulation
Blood Coagulation Disorders - therapy
Female
Fetal Growth Retardation - etiology
Fetus - drug effects
Fibrinogen - analysis
Fibrinogen - drug effects
Hemostasis - drug effects
Lung - physiopathology
Nadroparin - pharmacology
Placenta - drug effects
Pre-Eclampsia - blood
Pre-Eclampsia - etiology
Pre-Eclampsia - therapy
Pregnancy
Random Allocation
Rats
title Pharmacological correction of hemostasis-regulating function of the lungs in rats with uncomplicated pregnancy and experimental gestosis
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