Protective effect of carnosine on excitable structures of the auditory apparatus in albino rats with acute acoustic trauma

We studied the effect of natural antioxidant carnosine on Wistar rats with experimental acoustic trauma of the auditory apparatus. Repeated intraperitoneal injection of carnosine in a dose of 200 mg/kg 12 and 0.5 h before modeling of acute acoustic trauma decreased the severity of degenerative and a...

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Veröffentlicht in:	Bulletin of experimental biology and medicine 2004-01, Vol.137 (1), p.98-102
Hauptverfasser:	Zhuravskii, S G, Aleksandrova, L A, Ivanov, S A, Sirot, V S, Lopotko, A I, Zhloba, A A
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antioxidants - therapeutic use Carnosine - therapeutic use Cochlea - chemistry Cochlea - drug effects Cochlea - pathology Hair Cells, Auditory - pathology Hearing Loss, Noise-Induced - chemically induced Hearing Loss, Noise-Induced - pathology Hearing Loss, Noise-Induced - prevention & control Lipid Peroxidation - drug effects Malondialdehyde - analysis Rats Rats, Wistar Superoxide Dismutase - analysis
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