Combined effects of toxicants with various mechanisms of action and mechanical trauma on the immune system

Experiments on Wistar rats showed that the combined action of mechanical trauma and organophosphorus compound dimethyl dichlorovinyl phosphate a dose of 0.8 LD50 was accompanied by summation of their immunosuppressive effects. We observed an additive effect in relation to stimulation of the adrenal...

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Veröffentlicht in:	Bulletin of experimental biology and medicine 2002-06, Vol.133 (6), p.594
Hauptverfasser:	Zabrodskii, P F, Germanchuk, V G, Kirichuk, V F, Birbin, V S, Chuev, A N
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetonitriles - toxicity Acrylonitrile - toxicity Adrenal Cortex - drug effects Animals Corticosterone - blood Dichlorvos - poisoning Drug Interactions Immune System - drug effects Insecticides - poisoning Lethal Dose 50 Male Organophosphate Poisoning Rats Rats, Wistar Wounds and Injuries - immunology
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