Effect of peptide Vilon on the content of transforming growth factor-[beta] and permeability of microvessels during experimental chronic renal failure

We studied the effect of Vilon in rats 2, 4, and 6 months after the onset of chronic renal failure. Subcutaneous injection of Vilon significantly decreased serum concentration of transforming growth factor-β1 and permeability of mesenteric microvessels in rats 2 months after the onset of chronic ren...

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Veröffentlicht in:Bulletin of experimental biology and medicine 2005-01, Vol.139 (1), p.24
Hauptverfasser: Gavrisheva, N A, Malinin, V V, Ses', T P, Kozlov, K L, Panchenko, A V, A. Yu. Titkov
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container_start_page 24
container_title Bulletin of experimental biology and medicine
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creator Gavrisheva, N A
Malinin, V V
Ses', T P
Kozlov, K L
Panchenko, A V
A. Yu. Titkov
description We studied the effect of Vilon in rats 2, 4, and 6 months after the onset of chronic renal failure. Subcutaneous injection of Vilon significantly decreased serum concentration of transforming growth factor-β1 and permeability of mesenteric microvessels in rats 2 months after the onset of chronic renal failure. Our results indicate that the preparation produces a potent homeostatic effect in the early period of chronic renal failure.
doi_str_mv 10.1007/s10517-005-0202-9
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title Effect of peptide Vilon on the content of transforming growth factor-[beta] and permeability of microvessels during experimental chronic renal failure
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