Plasma NO-Binding Activity in Patients with Hematological Malignancies: Suppressive Effect of Glucocorticoids

Plasma NO-Binding Activity in Patients with Hematological Malignancies: Suppressive Effect of Glucocorticoids

Plasma NO-binding activity was studied in patients with various forms of hematological malignancies. The method used in the study quantitatively evaluated the plasma capacity to bind NO, which reflects the intensity of NO production and the degree of patient's stress resistance. Plasma NO-bindi...

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Veröffentlicht in:Bulletin of experimental biology and medicine 2006-10, Vol.142 (4), p.614
Hauptverfasser: Petukhov VI, Kalvinsh, I Y, Shestakova, I K, Domracheva IA, Kanepe, I Y, Stibel, R G, Romanova MA, Skesters, A P
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container_issue 4
container_start_page 614
container_title Bulletin of experimental biology and medicine
container_volume 142
creator Petukhov VI
Kalvinsh, I Y
Shestakova, I K
Domracheva IA
Kanepe, I Y
Stibel, R G
Romanova MA
Skesters, A P
description Plasma NO-binding activity was studied in patients with various forms of hematological malignancies. The method used in the study quantitatively evaluated the plasma capacity to bind NO, which reflects the intensity of NO production and the degree of patient's stress resistance. Plasma NO-binding activity significantly decreases in patients with hematological malignancies. Glucocorticoid treatment promotes the decrease in plasma NO-binding activity, which was dose-dependent.
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title Plasma NO-Binding Activity in Patients with Hematological Malignancies: Suppressive Effect of Glucocorticoids
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