$Sequential HLA‐haploidentical transplantation utilizing post‐transplantation cyclophosphamide for GvHD prophylaxis in high‐risk and relapsed/refractory AML/MDS$

Sequential HLA‐haploidentical transplantation utilizing post‐transplantation cyclophosphamide for GvHD prophylaxis in high‐risk and relapsed/refractory AML/MDS

This study evaluates the role of sequential therapy in HLA‐haploidentical transplantation (haplo‐HSCT) of high‐risk, relapsed/refractory AML/MDS. We analyzed the course of 33 adults with active disease at time of transplantation (AML n = 30; MDS n = 3; median age 58 years, range: 32‐71). Sequential...

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Veröffentlicht in:	American journal of hematology 2018-12, Vol.93 (12), p.1524-1531
Hauptverfasser:	Fraccaroli, Alessia, Prevalsek, Dusan, Fritsch, Susanne, Haebe, Sarah, Bücklein, Veit, Schulz, Christoph, Hubmann, Max, Stemmler, Hans‐Joachim, Ledderose, Georg, Hausmann, Andreas, Schmid, Christoph, Tischer, Johanna
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Chemotherapy Cyclophosphamide Cyclophosphamide - therapeutic use Diarrhea Disease-Free Survival Female Gastrointestinal tract Graft rejection Graft vs Host Disease - prevention & control Graft-versus-host reaction Hematology Hematopoietic Stem Cell Transplantation - methods Histocompatibility antigen HLA Humans Immunological tolerance Leukemia Leukemia, Myeloid, Acute - mortality Leukemia, Myeloid, Acute - therapy Male Middle Aged Mucositis Myelodysplastic Syndromes - mortality Myelodysplastic Syndromes - therapy Patients Prophylaxis Remission Salvage Therapy - methods Stem cell transplantation Toxicity Transplantation, Haploidentical - methods Treatment Outcome
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