Negative effect of nitric oxide on shorteningfrequency relationship in cardiac myocytes is diminished after simulated ischemia-reperfusion

Increasing stimulation rate increases function in cardiac myocytes and nitric oxide and cyclic GMP inhibit this effect. We tested the hypothesis that myocyte stunning would blunt both the effects of increases in rate and of nitric oxide and cyclic GMP. Ventricular myocytes from 11 rabbits were used...

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Veröffentlicht in:Basic research in cardiology 2003-09, Vol.98 (5), p.311-318
Hauptverfasser: Weiss, Harvey R., Gandhi, Ankur, Scholz, Peter M.
Format: Artikel
Sprache:eng
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