Endotoxin-induced effects on platelets and monocytes in an in vivo model of inflammation

Chronic inflammation is a major contributing factor to atherosclerosis and various markers of inflammation, fibrinolysis and coagulation are upregulated in patients with established atherosclerotic disease. The aim of this study was to investigate the direct and short-term effects of inflammation on...

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Veröffentlicht in:	Basic research in cardiology 2007-09, Vol.102 (5), p.460-466
Hauptverfasser:	Kälsch, Thorsten, Elmas, Elif, Nguyen, Xuan Duc, Suvajac, Nenad, Klüter, Harald, Borggrefe, Martin, Dempfle, Carl-Erik
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Atherosclerosis - chemically induced Atherosclerosis - immunology Blood Platelets - drug effects Blood Platelets - immunology Blood Platelets - metabolism CD40 Ligand - metabolism Endotoxemia - chemically induced Endotoxemia - immunology Humans Lipopolysaccharides - adverse effects Lipopolysaccharides - immunology Male Monocytes - drug effects Monocytes - immunology Monocytes - metabolism P-Selectin - metabolism Platelet Activation - drug effects Platelet Activation - immunology Thromboplastin - metabolism Up-Regulation - drug effects Up-Regulation - immunology
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