Expression of the cytoplasmic domain of [beta]1 integrin induces apoptosis in adult rat ventricular myocytes (ARVM) via the involvement of caspase-8 and mitochondrial death pathway

Stimulation of β-adrenergic receptor (β-AR) induces cardiac myocyte apoptosis. Integrins, a family of cell-surface receptors, play an important role in the regulation of cardiac myocyte apoptosis and ventricular remodeling. Cleavage of extracellular domain of β1 integrin, also called integrin sheddi...

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Veröffentlicht in:	Basic research in cardiology 2006-11, Vol.101 (6), p.485
1. Verfasser:	Bindu MenonPrasanna KrishnamurthyEkaterina KaverinaJennifer N. JohnsonRobert S. RossMahipal SinghKrishna Singh
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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