Effect of 17β-estradiol administration on hepatic expression of glutamine synthetase, β-catenin, and GPR30 in young and aged beef cows

To test the hypothesis that increased circulating estradiol increases hepatic glutamine synthetase (GS) content in young and aged cows, and two nonclassical nongenomic estradiol pathway intermediates [β-catenin, G protein-coupled receptor 30 (GPR30)], 12 young (3–4 yr) and 12 aged (≥8 yr) cows were...

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Veröffentlicht in:	Canadian journal of animal science 2017-06, Vol.97 (2), p.281-289, Article CJAS-2016-0002
Hauptverfasser:	Miles, Edwena D., McBride, Brian W., Bridges, Phillip J., Matthews, James C.
Format:	Artikel
Sprache:	eng
Schlagworte:	17β-Estradiol Age aging Beef cattle boeufs cattle estrogen G protein-coupled receptor 30 (GPR30) Glutamate-ammonia ligase Glutamine glutamine synthetase glutamine synthétase GROWTH AND DEVELOPMENT Guanine nucleotide-binding protein Implants Intermediates Liver mRNA oestrogènes Progesterone Proteins récepteur 30 couplé à la protéine G (GPR30) Sex hormones Transplants & implants Variance analysis vieillissement β-Catenin β-caténine
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