Lung Cancer in Chromate-Exposed Aerospace Workers
A retrospective cohort study evaluated the nsk of lung cancer in aerospace workers with a minimum of 6 months' employment in jobs with chromium [VI] exposure (n = 2429). Standardized incidence ratios (SIR) estimated the risk of lung cancer by duration of employment in chromate-exposure jobs and...
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Veröffentlicht in: | Journal of occupational and environmental medicine 1996-12, Vol.38 (12), p.1253-1258 |
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creator | Alexander, Bruce H. Checkoway, Harvey Wechsler, Laurence Heyer, Nicholas J. Muhm, J. Michael O'Keeffe, Thomas P. |
description | A retrospective cohort study evaluated the nsk of lung cancer in aerospace workers with a minimum of 6 months' employment in jobs with chromium [VI] exposure (n = 2429). Standardized incidence ratios (SIR) estimated the risk of lung cancer by duration of employment in chromate-exposure jobs and cumulative exposure based on industri hygiene and work-history data. The overall SIR for lung cancer was 0.8 (observed [Obs] = 15). Lung cancer risk was inversely related to estimates of cumulative chromate exposure and duration of employmen as a painter. Although based on few cases, an elevated lung cancer r was found in subjects who had worked for 5 or more years as a chrom plater or surface processor tank tender (Obs = 2, SIR = 1.9) and sander/masker or polisher (Obs = 3, SIR = 2.7). A clear association was not observed between chromate exposure and the risk of lung canc in this population of workers. |
doi_str_mv | 10.1097/00043764-199612000-00011 |
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Michael ; O'Keeffe, Thomas P.</creator><creatorcontrib>Alexander, Bruce H. ; Checkoway, Harvey ; Wechsler, Laurence ; Heyer, Nicholas J. ; Muhm, J. Michael ; O'Keeffe, Thomas P.</creatorcontrib><description>A retrospective cohort study evaluated the nsk of lung cancer in aerospace workers with a minimum of 6 months' employment in jobs with chromium [VI] exposure (n = 2429). Standardized incidence ratios (SIR) estimated the risk of lung cancer by duration of employment in chromate-exposure jobs and cumulative exposure based on industri hygiene and work-history data. The overall SIR for lung cancer was 0.8 (observed [Obs] = 15). Lung cancer risk was inversely related to estimates of cumulative chromate exposure and duration of employmen as a painter. Although based on few cases, an elevated lung cancer r was found in subjects who had worked for 5 or more years as a chrom plater or surface processor tank tender (Obs = 2, SIR = 1.9) and sander/masker or polisher (Obs = 3, SIR = 2.7). A clear association was not observed between chromate exposure and the risk of lung canc in this population of workers.</description><identifier>ISSN: 1076-2752</identifier><identifier>EISSN: 1536-5948</identifier><identifier>DOI: 10.1097/00043764-199612000-00011</identifier><identifier>PMID: 8978517</identifier><identifier>CODEN: JOEMFM</identifier><language>eng</language><publisher>Hagerstown, MD: Williams & Wilkins</publisher><subject>Adult ; Aerosols - adverse effects ; Aerospace industry ; Air Pollution, Indoor - adverse effects ; Aviation ; Biological and medical sciences ; Chromates - adverse effects ; Chromium ; Dust - adverse effects ; Female ; Follow-Up Studies ; Humans ; Incidence ; Lung cancer ; Lung Neoplasms - epidemiology ; Male ; Medical sciences ; Middle Aged ; Occupational Exposure - adverse effects ; Occupational hazards ; Occupations ; ORIGINAL ARTICLES ; Paint - adverse effects ; Pneumology ; Retrospective Studies ; Time Factors ; Tumors of the respiratory system and mediastinum ; Washington - epidemiology</subject><ispartof>Journal of occupational and environmental medicine, 1996-12, Vol.38 (12), p.1253-1258</ispartof><rights>Copyright © 1996 American College of Occupational and Environmental Medicine</rights><rights>Williams & Wilkins 1996. All Rights Reserved.</rights><rights>1997 INIST-CNRS</rights><rights>Copyright Lippincott Williams & Wilkins Dec 1996</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4331-fda47be6ab4fa6c16d28a8ab7030b71aad6a27dde90e1e079073faac289c54d83</citedby><cites>FETCH-LOGICAL-c4331-fda47be6ab4fa6c16d28a8ab7030b71aad6a27dde90e1e079073faac289c54d83</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.jstor.org/stable/pdf/44994875$$EPDF$$P50$$Gjstor$$H</linktopdf><linktohtml>$$Uhttps://www.jstor.org/stable/44994875$$EHTML$$P50$$Gjstor$$H</linktohtml><link.rule.ids>314,776,780,799,27903,27904,57996,58229</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=2524771$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/8978517$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Alexander, Bruce H.</creatorcontrib><creatorcontrib>Checkoway, Harvey</creatorcontrib><creatorcontrib>Wechsler, Laurence</creatorcontrib><creatorcontrib>Heyer, Nicholas J.</creatorcontrib><creatorcontrib>Muhm, J. Michael</creatorcontrib><creatorcontrib>O'Keeffe, Thomas P.</creatorcontrib><title>Lung Cancer in Chromate-Exposed Aerospace Workers</title><title>Journal of occupational and environmental medicine</title><addtitle>J Occup Environ Med</addtitle><description>A retrospective cohort study evaluated the nsk of lung cancer in aerospace workers with a minimum of 6 months' employment in jobs with chromium [VI] exposure (n = 2429). Standardized incidence ratios (SIR) estimated the risk of lung cancer by duration of employment in chromate-exposure jobs and cumulative exposure based on industri hygiene and work-history data. The overall SIR for lung cancer was 0.8 (observed [Obs] = 15). Lung cancer risk was inversely related to estimates of cumulative chromate exposure and duration of employmen as a painter. Although based on few cases, an elevated lung cancer r was found in subjects who had worked for 5 or more years as a chrom plater or surface processor tank tender (Obs = 2, SIR = 1.9) and sander/masker or polisher (Obs = 3, SIR = 2.7). A clear association was not observed between chromate exposure and the risk of lung canc in this population of workers.</description><subject>Adult</subject><subject>Aerosols - adverse effects</subject><subject>Aerospace industry</subject><subject>Air Pollution, Indoor - adverse effects</subject><subject>Aviation</subject><subject>Biological and medical sciences</subject><subject>Chromates - adverse effects</subject><subject>Chromium</subject><subject>Dust - adverse effects</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Humans</subject><subject>Incidence</subject><subject>Lung cancer</subject><subject>Lung Neoplasms - epidemiology</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Occupational Exposure - adverse effects</subject><subject>Occupational hazards</subject><subject>Occupations</subject><subject>ORIGINAL ARTICLES</subject><subject>Paint - adverse effects</subject><subject>Pneumology</subject><subject>Retrospective Studies</subject><subject>Time Factors</subject><subject>Tumors of the respiratory system and mediastinum</subject><subject>Washington - epidemiology</subject><issn>1076-2752</issn><issn>1536-5948</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1996</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kU1LxDAQhoMoq67-BKGI12qS5vO4lPUDFrwoHsO0Td2PbluTltV_b9at9eQhTIZ5553hGYQigm8J1vIOY8wSKVhMtBaEhjQOj5AjdEZ4ImKumToOfyxFTCWnp-jc-3VQcIL5BE2UlooTeYbIoq_foxTq3LpoVUfp0jVb6Gw8_2wbb4toZl3jW8ht9Na4jXX-Ap2UUHl7OcQper2fv6SP8eL54SmdLeKcJQmJywKYzKyAjJUgciIKqkBBJnGCM0kACgFUFoXV2BKLpcYyKQFyqnTOWaGSKbo--Lau-eit78y66V0dRhpKqFCYCRxE6iDKw5be2dK0brUF92UINntS5peUGUmZH1Kh9Wrw77OtLcbGAU2o3wx18DlUpQuMVn6UUU6ZlHsbdpDtmqoLeDZVv7POLC1U3dL8d6e_6WvfNW50ZUyHy0mefANLhIg0</recordid><startdate>199612</startdate><enddate>199612</enddate><creator>Alexander, Bruce H.</creator><creator>Checkoway, Harvey</creator><creator>Wechsler, Laurence</creator><creator>Heyer, Nicholas J.</creator><creator>Muhm, J. Michael</creator><creator>O'Keeffe, Thomas P.</creator><general>Williams & Wilkins</general><general>Lippincott Williams & Wilkins</general><general>Lippincott Williams & Wilkins Ovid Technologies</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T2</scope><scope>7U7</scope><scope>7U9</scope><scope>C1K</scope><scope>H94</scope><scope>K9.</scope></search><sort><creationdate>199612</creationdate><title>Lung Cancer in Chromate-Exposed Aerospace Workers</title><author>Alexander, Bruce H. ; Checkoway, Harvey ; Wechsler, Laurence ; Heyer, Nicholas J. ; Muhm, J. Michael ; O'Keeffe, Thomas P.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4331-fda47be6ab4fa6c16d28a8ab7030b71aad6a27dde90e1e079073faac289c54d83</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1996</creationdate><topic>Adult</topic><topic>Aerosols - adverse effects</topic><topic>Aerospace industry</topic><topic>Air Pollution, Indoor - adverse effects</topic><topic>Aviation</topic><topic>Biological and medical sciences</topic><topic>Chromates - adverse effects</topic><topic>Chromium</topic><topic>Dust - adverse effects</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>Humans</topic><topic>Incidence</topic><topic>Lung cancer</topic><topic>Lung Neoplasms - epidemiology</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Occupational Exposure - adverse effects</topic><topic>Occupational hazards</topic><topic>Occupations</topic><topic>ORIGINAL ARTICLES</topic><topic>Paint - adverse effects</topic><topic>Pneumology</topic><topic>Retrospective Studies</topic><topic>Time Factors</topic><topic>Tumors of the respiratory system and mediastinum</topic><topic>Washington - epidemiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Alexander, Bruce H.</creatorcontrib><creatorcontrib>Checkoway, Harvey</creatorcontrib><creatorcontrib>Wechsler, Laurence</creatorcontrib><creatorcontrib>Heyer, Nicholas J.</creatorcontrib><creatorcontrib>Muhm, J. Michael</creatorcontrib><creatorcontrib>O'Keeffe, Thomas P.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Health and Safety Science Abstracts (Full archive)</collection><collection>Toxicology Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Environmental Sciences and Pollution Management</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><jtitle>Journal of occupational and environmental medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Alexander, Bruce H.</au><au>Checkoway, Harvey</au><au>Wechsler, Laurence</au><au>Heyer, Nicholas J.</au><au>Muhm, J. Michael</au><au>O'Keeffe, Thomas P.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Lung Cancer in Chromate-Exposed Aerospace Workers</atitle><jtitle>Journal of occupational and environmental medicine</jtitle><addtitle>J Occup Environ Med</addtitle><date>1996-12</date><risdate>1996</risdate><volume>38</volume><issue>12</issue><spage>1253</spage><epage>1258</epage><pages>1253-1258</pages><issn>1076-2752</issn><eissn>1536-5948</eissn><coden>JOEMFM</coden><abstract>A retrospective cohort study evaluated the nsk of lung cancer in aerospace workers with a minimum of 6 months' employment in jobs with chromium [VI] exposure (n = 2429). Standardized incidence ratios (SIR) estimated the risk of lung cancer by duration of employment in chromate-exposure jobs and cumulative exposure based on industri hygiene and work-history data. The overall SIR for lung cancer was 0.8 (observed [Obs] = 15). Lung cancer risk was inversely related to estimates of cumulative chromate exposure and duration of employmen as a painter. Although based on few cases, an elevated lung cancer r was found in subjects who had worked for 5 or more years as a chrom plater or surface processor tank tender (Obs = 2, SIR = 1.9) and sander/masker or polisher (Obs = 3, SIR = 2.7). A clear association was not observed between chromate exposure and the risk of lung canc in this population of workers.</abstract><cop>Hagerstown, MD</cop><pub>Williams & Wilkins</pub><pmid>8978517</pmid><doi>10.1097/00043764-199612000-00011</doi><tpages>6</tpages></addata></record> |
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subjects | Adult Aerosols - adverse effects Aerospace industry Air Pollution, Indoor - adverse effects Aviation Biological and medical sciences Chromates - adverse effects Chromium Dust - adverse effects Female Follow-Up Studies Humans Incidence Lung cancer Lung Neoplasms - epidemiology Male Medical sciences Middle Aged Occupational Exposure - adverse effects Occupational hazards Occupations ORIGINAL ARTICLES Paint - adverse effects Pneumology Retrospective Studies Time Factors Tumors of the respiratory system and mediastinum Washington - epidemiology |
title | Lung Cancer in Chromate-Exposed Aerospace Workers |
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