Intracoronary adenovirus-mediated delivery and overexpression of the (beta(2))-adrenergic receptor in the heart: Prospects for molecular ventricular assistance

BACKGROUND: Genetic modulation of ventricular function may offer a novel therapeutic strategy for patients with congestive heart failure. Myocardial overexpression of beta(2)-adrenergic receptors (beta(2)ARs) has been shown to enhance contractility in transgenic mice and reverse signaling abnormalit...

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Veröffentlicht in:	Circulation (New York, N.Y.) N.Y.), 2000-02, Vol.101 (4), p.408
Hauptverfasser:	Shah, Ashish S, Lilly, R Eric, Kypson, Alan P, Tai, Oliver
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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