A pilot study of dose intense doxorubicin and cyclophosphamide followed by infusional paclitaxel in high-risk primary breast cancer

We conducted a pilot study of dose dense doxorubicin and cyclophosphamide (AC) combination chemotherapy followed by infusional paclitaxel (T) in primary breast cancer to determine its safety and feasibility. Twenty-two subjects (10 with stage II and > or = 4 positive lymph nodes, and 12 with stag...

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Veröffentlicht in:	Breast cancer research and treatment 2003-09, Vol.81 (1), p.41-51
Hauptverfasser:	ZUJEWSKI, Jo Anne, ENG-WONG, Jennifer, O'SHAUGHNESSY, Joyce, VENZON, David, CHOW, Catherine, DANFORTH, David, KOHLER, David R, CUSACK, Georgia, RISEBERG, David, COWAN, Kenneth H
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibiotics, Antineoplastic - administration & dosage Antineoplastic agents Antineoplastic Agents, Alkylating - administration & dosage Antineoplastic Agents, Phytogenic - administration & dosage Antineoplastic Combined Chemotherapy Protocols - adverse effects Antineoplastic Combined Chemotherapy Protocols - therapeutic use Biological and medical sciences Breast cancer Breast Neoplasms - drug therapy Cancer research Cancer therapies Chemotherapy Chemotherapy, Adjuvant Cyclophosphamide - administration & dosage Doxorubicin - administration & dosage Drug Administration Schedule Female Humans Medical sciences Neutropenia - chemically induced Paclitaxel - administration & dosage Pharmacology. Drug treatments Pilot Projects Treatment Outcome
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