Association between the T6459C point mutation of the mitochondrial MT ‐ CO 1 gene and susceptibility to sepsis among Chinese Han people

To search for an association between sepsis and mitochondrial genetic basis, we began our study. In this study, a proband harbouring mitochondrial T6459C mutation with sepsis and his Chinese Han pedigree including 7 members of 3 generations were enrolled. General information, blood parameters and mi...

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Veröffentlicht in:	Journal of cellular and molecular medicine 2018-11, Vol.22 (11), p.5257-5264
Hauptverfasser:	Shen, Xiaodong, Han, Guoxin, Li, Shuoshuo, Song, Yang, Shen, Hong, Zhai, Yongzhi, Wang, Yingchan, Zhang, Fei, Dong, Ning, Li, Tanshi, Yao, Yongming, Zhu, Haiyan
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine triphosphate Apoptosis ATP Blood coagulation Lipopolysaccharides Membrane potential Mitochondria Mitochondrial DNA Mutation Pedigree Point mutation Reactive oxygen species Scanning Sepsis Stimulation
Online-Zugang:	Volltext
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