An observation of histological evidence on internal organ damages in mice caused by repeated exposures to motorcycle emissions
Motor vehicle emissions have been identified as a source of ultrafine particles, which have significant impacts on human health. Repeated and prolonged exposure to ultrafine particles may have a significant association with organ damage. Here, we evaluated the correlation between repeated exposure t...
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| creator | Wardoyo, Arinto Y. P. Juswono, Unggul P. Noor, Johan A. E. |
| description | Motor vehicle emissions have been identified as a source of ultrafine particles, which have significant impacts on human health. Repeated and prolonged exposure to ultrafine particles may have a significant association with organ damage. Here, we evaluated the correlation between repeated exposure to ultrafine particles and organ damage in mice. Motorcycle emissions were injected into an exposure chamber with mice for a period of 20 seconds. This treatment was conducted over 10 days. The mice were sacrificed on the 2nd, 4th, 6th, 8th, and 10th days for organ preparations. Based on the results, motorcycle emission exposure caused organ damage in mice, with different severities depending on the organ. The highest damage was found for the lung, followed by the kidney, erythrocytes, and liver. |
| doi_str_mv | 10.1063/1.4983418 |
| format | Conference Proceeding |
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P. ; Juswono, Unggul P. ; Noor, Johan A. E.</creator><contributor>Hamid, Nazefah Abdul ; Mustafa, Irfan ; Shrestha, Bhupal Govinda</contributor><creatorcontrib>Wardoyo, Arinto Y. P. ; Juswono, Unggul P. ; Noor, Johan A. E. ; Hamid, Nazefah Abdul ; Mustafa, Irfan ; Shrestha, Bhupal Govinda</creatorcontrib><description>Motor vehicle emissions have been identified as a source of ultrafine particles, which have significant impacts on human health. Repeated and prolonged exposure to ultrafine particles may have a significant association with organ damage. Here, we evaluated the correlation between repeated exposure to ultrafine particles and organ damage in mice. Motorcycle emissions were injected into an exposure chamber with mice for a period of 20 seconds. This treatment was conducted over 10 days. The mice were sacrificed on the 2nd, 4th, 6th, 8th, and 10th days for organ preparations. 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The mice were sacrificed on the 2nd, 4th, 6th, 8th, and 10th days for organ preparations. Based on the results, motorcycle emission exposure caused organ damage in mice, with different severities depending on the organ. The highest damage was found for the lung, followed by the kidney, erythrocytes, and liver.</abstract><cop>Melville</cop><pub>American Institute of Physics</pub><doi>10.1063/1.4983418</doi><tpages>11</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0094-243X |
| ispartof | AIP conference proceedings, 2017, Vol.1844 (1) |
| issn | 0094-243X 1551-7616 |
| language | eng |
| recordid | cdi_proquest_journals_2124499916 |
| source | AIP Journals Complete |
| subjects | Airborne particulates Damage assessment Erythrocytes Exposure Health risk assessment Kidneys Liver Mice Motor vehicles Motorcycles Ultrafines Vehicle emissions |
| title | An observation of histological evidence on internal organ damages in mice caused by repeated exposures to motorcycle emissions |
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