Oxidative DNA Damage and Repair in Experimental Atherosclerosis Are Reversed by Dietary Lipid Lowering

Increased oxidative stress is a major characteristic of hypercholesterolemia-induced atherosclerosis. The oxidative environment is mainly created by the production of reactive oxygen species, which are assumed to mediate vascular tissue injury. Oxidative DNA damage resulting from free radical attack...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Circulation research 2001-04, Vol.88 (7), p.733-739
Hauptverfasser:	Martinet, Wim, Knaapen, Michiel W.M, De Meyer, Guido R.Y, Herman, Arnold G, Kockx, Mark M
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Aorta - metabolism Aorta - pathology Arteriosclerosis - diet therapy Arteriosclerosis - metabolism Arteriosclerosis - pathology Atherosclerosis (general aspects, experimental research) Biological and medical sciences Blood and lymphatic vessels Blotting, Western Cardiology. Vascular system Cholesterol - blood Cholesterol - metabolism Cholesterol - pharmacology Comet Assay Diet, Atherogenic Dietary Fats - metabolism Dietary Fats - pharmacology Disease Models, Animal DNA - metabolism DNA Damage - drug effects DNA Ligases - metabolism DNA Repair - drug effects Immunohistochemistry Lipids - blood Male Medical sciences Oxidative Stress Rabbits Treatment Outcome
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!