Autonomous and Growth Factor–Induced Hypertrophy in Cultured Neonatal Mouse Cardiac Myocytes: Comparison With Rat

ABSTRACT—Cultured neonatal rat cardiac myocytes have been used extensively to study cellular and molecular mechanisms of cardiac hypertrophy. However, there are only a few studies in cultured mouse myocytes despite the increasing use of genetically engineered mouse models of cardiac hypertrophy. The...

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Veröffentlicht in:	Circulation research 2000-10, Vol.87 (9), p.781-788
Hauptverfasser:	Deng, Xing-Fei, Rokosh, D Gregg, Simpson, Paul C
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenergic alpha-Agonists - pharmacology Animals Animals, Newborn Atrial Natriuretic Factor - genetics Atrial Natriuretic Factor - metabolism Biological and medical sciences Cardiology. Vascular system Cells, Cultured Dinoprost - pharmacology Endothelin-1 - pharmacology Fetus Growth Inhibitors - pharmacology Growth Substances - pharmacology Heart Heart - drug effects Heart - embryology Heart failure, cardiogenic pulmonary edema, cardiac enlargement Hypertrophy Interleukin-1 - pharmacology Interleukin-6 Leukemia Inhibitory Factor Lymphokines - pharmacology Medical sciences Mice Microscopy, Phase-Contrast Models, Animal Myocardium - pathology Myosin Heavy Chains - genetics Myosin Heavy Chains - metabolism Myosins - analysis Norepinephrine - pharmacology Phenotype Phenylalanine - analysis Protein Biosynthesis Proteins - chemistry Rats RNA, Messenger - analysis Tetradecanoylphorbol Acetate - pharmacology Triiodothyronine - pharmacology
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