Desphosphorylation and intracellular redistribution of ventricular connexin43 during electrical uncoupling induced by ischemia

Electrical uncoupling at gap junctions during acute myocardial ischemia contributes to conduction abnormalities and reentrant arrhythmias. Increased levels of intracellular Ca(2+) and H(+) and accumulation of amphipathic lipid metabolites during ischemia promote uncoupling, but other mechanisms may...

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Veröffentlicht in:	Circulation research 2000-10, Vol.87 (8), p.656
Hauptverfasser:	Beardslee, Michael A, Lerner, Deborah L, Tadros, Peter N, Laing, James G
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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