Effects of 60 kDa prolactin and estradiol on metabolism and cell survival in cervical cancer: Co‑expression of their hormonal receptors during cancer progression

Estrogens and estrogen receptors (ERs), such as ERα and ERβ, prolactin (PRL) and prolactin receptor (PRLR) have been reported to be involved in the physiopathology of uterine cervical cancer (UCC). The 60 kDa PRL is an isoform of PRL, which is produced by UCC‑derived cells. The present study aimed t...

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Veröffentlicht in:	Oncology reports 2018-12, Vol.40 (6), p.3781-3793
Hauptverfasser:	Riera-Leal, Annie, Ramírez De Arellano, Adrián, Ramírez-López, Inocencia Guadalupe, Lopez-Pulido, Edgar I, Dávila Rodríguez, Judith R, Macías-Barragan, José G, Ortiz-Lazareno, Pablo César, Jave-Suárez, Luis Felipe, Artaza-Irigaray, Cristina, Del Toro Arreola, Susana, Montoya-Buelna, Margarita, Muñoz-Valle, José Francisco, Pereira-Suárez, Ana Laura
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Breast cancer Cell growth Cell Line, Tumor Cell Proliferation Cell Survival Cervical cancer Disease Disease Progression Down-Regulation Estradiol - pharmacology Estrogen Receptor alpha - metabolism Estrogen Receptor beta - metabolism Estrogens Female Gene Expression Regulation, Neoplastic - drug effects HeLa Cells Hormones Human papillomavirus Humans Infections Ki-67 Antigen - metabolism Lymphoma Metabolism Prolactin - pharmacology Protein Isoforms - pharmacology Proteins Receptors, Estrogen - metabolism Receptors, Prolactin - metabolism Studies Uterine Cervical Neoplasms - metabolism
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