Discrimination of molecular thin films by surface-sensitive time-resolved optical spectroscopy
An optical discrimination technique, tailored to nanometric-sized, low optical absorbance molecular complexes adhering to thin metal films, is proposed and demonstrated. It is based on a time-resolved evanescent-wave detection scheme in conjunction with hierarchical cluster analysis and principal va...
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Veröffentlicht in: | Applied physics letters 2015-10, Vol.107 (16) |
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creator | Peli, Simone Nembrini, Nicola Damin, Francesco Chiari, Marcella Giannetti, Claudio Banfi, Francesco Ferrini, Gabriele |
description | An optical discrimination technique, tailored to nanometric-sized, low optical absorbance molecular complexes adhering to thin metal films, is proposed and demonstrated. It is based on a time-resolved evanescent-wave detection scheme in conjunction with hierarchical cluster analysis and principal value decomposition. The present approach aims to differentiate among molecular films based on statistical methods, without using previous detailed knowledge of the physical mechanisms responsible for the detected signal. The technique is open to integration in lab-on-a-chip architectures and nanoscopy platforms for applications ranging from medical screening to material diagnostics. |
doi_str_mv | 10.1063/1.4934216 |
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The technique is open to integration in lab-on-a-chip architectures and nanoscopy platforms for applications ranging from medical screening to material diagnostics.</description><subject>Applied physics</subject><subject>Cluster analysis</subject><subject>Coordination compounds</subject><subject>Discrimination</subject><subject>Medical materials</subject><subject>Medical screening</subject><subject>Metal films</subject><subject>Statistical methods</subject><subject>Thin films</subject><issn>0003-6951</issn><issn>1077-3118</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><recordid>eNotUM1LwzAcDaLgnB78DwKePGTml3RJc5T5CQMvejWkaYIZbVOTdLD_3sp2ejx4vC-EboGugAr-AKtK8YqBOEMLoFISDlCfowWllBOh1nCJrnLezXTNOF-g76eQbQp9GEwJccDR4z52zk6dSbj8hAH70PUZNwecp-SNdSS7IYcS9g6X0DuSXI7d3rU4jiVY0-E8OltSzDaOh2t04U2X3c0Jl-jr5flz80a2H6_vm8ctsUyxQpxYt8pJwyUwL01lwUqhjKBKKMkbb71lbWNUW0nvK9YaaxVzlWih5iC45Et0d_QdU_ydXC56F6c0zJGaAeO14DWrZtX9UWXnejk5r8d5ukkHDVT_36dBn-7jfzY4Y34</recordid><startdate>20151019</startdate><enddate>20151019</enddate><creator>Peli, Simone</creator><creator>Nembrini, Nicola</creator><creator>Damin, Francesco</creator><creator>Chiari, Marcella</creator><creator>Giannetti, Claudio</creator><creator>Banfi, Francesco</creator><creator>Ferrini, Gabriele</creator><general>American Institute of Physics</general><scope>AAYXX</scope><scope>CITATION</scope><scope>8FD</scope><scope>H8D</scope><scope>L7M</scope><orcidid>https://orcid.org/0000-0002-7465-8417</orcidid></search><sort><creationdate>20151019</creationdate><title>Discrimination of molecular thin films by surface-sensitive time-resolved optical spectroscopy</title><author>Peli, Simone ; Nembrini, Nicola ; Damin, Francesco ; Chiari, Marcella ; Giannetti, Claudio ; Banfi, Francesco ; Ferrini, Gabriele</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c292t-e65d9e7a3712f7a4c1c769a6096973bfcfc2dba9d47ff42dacc92e46d18316373</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>Applied physics</topic><topic>Cluster analysis</topic><topic>Coordination compounds</topic><topic>Discrimination</topic><topic>Medical materials</topic><topic>Medical screening</topic><topic>Metal films</topic><topic>Statistical methods</topic><topic>Thin films</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Peli, Simone</creatorcontrib><creatorcontrib>Nembrini, Nicola</creatorcontrib><creatorcontrib>Damin, Francesco</creatorcontrib><creatorcontrib>Chiari, Marcella</creatorcontrib><creatorcontrib>Giannetti, Claudio</creatorcontrib><creatorcontrib>Banfi, Francesco</creatorcontrib><creatorcontrib>Ferrini, Gabriele</creatorcontrib><collection>CrossRef</collection><collection>Technology Research Database</collection><collection>Aerospace Database</collection><collection>Advanced Technologies Database with Aerospace</collection><jtitle>Applied physics letters</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Peli, Simone</au><au>Nembrini, Nicola</au><au>Damin, Francesco</au><au>Chiari, Marcella</au><au>Giannetti, Claudio</au><au>Banfi, Francesco</au><au>Ferrini, Gabriele</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Discrimination of molecular thin films by surface-sensitive time-resolved optical spectroscopy</atitle><jtitle>Applied physics letters</jtitle><date>2015-10-19</date><risdate>2015</risdate><volume>107</volume><issue>16</issue><issn>0003-6951</issn><eissn>1077-3118</eissn><abstract>An optical discrimination technique, tailored to nanometric-sized, low optical absorbance molecular complexes adhering to thin metal films, is proposed and demonstrated. 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source | AIP Journals Complete; Alma/SFX Local Collection |
subjects | Applied physics Cluster analysis Coordination compounds Discrimination Medical materials Medical screening Metal films Statistical methods Thin films |
title | Discrimination of molecular thin films by surface-sensitive time-resolved optical spectroscopy |
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