Pharmacokinetics and time-course of D^sub 2^ receptor occupancy induced by atypical antipsychotics in stabilized schizophrenic patients

The sup123I-IBZM SPECT measured Dsub2 receptor occupancy (Dsub2RO) in chronically dosed, stabilized schizophrenic patients and its relationship with antipsychotic (AP) pharmacokinetics (PK) over time is still unclear. The aims of this study were: 1) To define the relationship between striatal Dsub2...

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Veröffentlicht in:Journal of psychopharmacology (Oxford) 2008-11, Vol.22 (8), p.882
Hauptverfasser: Catafau, AM, Penengo, MM, Nucci, G, Bullich, S, Corripio, I, Parellada, E, García-Ribera, C, Gomeni, R, Merlo-Pich, E
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Sprache:eng
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