Synthesis and Study of Antimicrobial Activity of Some New 3-(-Hydroxy-5-Methylphenyl)-4-Benzoyl-5-Phenylpyrazole
3-Aroyl-6-methyl flavones (Ia-f) were allowed to react with hydrozine hydrochloride in DMSO containing piperidine to give the corresponding 3-2-hydroxyphenyl-5-methyphenyl)-4-aroyl 5-arylpyrazoles (IIa-f) Their structural assignments are based on elemental analysis, spectral data (ir, uv and nmr) an...
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| Veröffentlicht in: | Oriental journal of chemistry 2008-01, Vol.24 (2), p.717 |
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| creator | Junghare, Neeta A Bhise, Madhuri P chincholkar, M M Bhise, P R |
| description | 3-Aroyl-6-methyl flavones (Ia-f) were allowed to react with hydrozine hydrochloride in DMSO containing piperidine to give the corresponding 3-2-hydroxyphenyl-5-methyphenyl)-4-aroyl 5-arylpyrazoles (IIa-f) Their structural assignments are based on elemental analysis, spectral data (ir, uv and nmr) and chemical properties. All these compounds were tested in vitro for their antimicrobial (antibacterial and antifungal) activity by disk diffusion against gram positive, gram negative bacteria and fungi. In some of the compounds the results are found to be encouraging. |
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| ispartof | Oriental journal of chemistry, 2008-01, Vol.24 (2), p.717 |
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| language | eng |
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| subjects | Antimicrobial agents Chemical compounds Chemical properties Fungicides Infrared radiation NMR Nuclear magnetic resonance Organic chemistry Piperidine |
| title | Synthesis and Study of Antimicrobial Activity of Some New 3-(-Hydroxy-5-Methylphenyl)-4-Benzoyl-5-Phenylpyrazole |
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