Micro-pelletizing of pharmaceutical HME formulations using a die face pelletizer

Hot melt extrusion (HME) is increasingly used in the pharmaceutical industry as it has significant potential for overcoming challenges associated with poorly soluble drug molecules via amorphous solid dispersion (ASD) formation [1]. Due to the increased solubility ASDs show significant higher bioava...

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Bibliographische Detailangaben

Hauptverfasser:	Witschnigg, A., Koscher, G., Treffer, D., Mürb, R., Laske, S., Khinast, J.
Format:	Tagungsbericht
Sprache:	eng
Schlagworte:	Batch processing Bioavailability Decoupling Deformation Extrusion dies Formulations Injection molding Pelleting Pellets Pharmaceutical industry Pharmaceuticals Polymers Surface tension
Online-Zugang:	Volltext
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