Bromination of Acetanilide

A general procedure for bromination of aromatic compounds activated with electron donating substituents such as acetamido, hydroxyl, or ether groups is described. Bromine is generated in situ from potassium bromate and hydrobromic acid. This procedure avoids the hazards associated with direct handli...

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Veröffentlicht in:Journal of chemical education 1996-03, Vol.73 (3), p.267
1. Verfasser: Schatz, Paul F
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container_title Journal of chemical education
container_volume 73
creator Schatz, Paul F
description A general procedure for bromination of aromatic compounds activated with electron donating substituents such as acetamido, hydroxyl, or ether groups is described. Bromine is generated in situ from potassium bromate and hydrobromic acid. This procedure avoids the hazards associated with direct handling of bromine or bromine solutions. The results from seven aromatic ethers and anilides are reported.
doi_str_mv 10.1021/ed073p267
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1938-1328
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subjects Acetanilide
Aromatic compounds
Bromination
Bromine
Bromine compounds
Chemical reactions
Experiments
Ions
Laboratories
Organic chemistry
Oxidation
title Bromination of Acetanilide
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