Bromination of Acetanilide

Bromination of Acetanilide

A general procedure for bromination of aromatic compounds activated with electron donating substituents such as acetamido, hydroxyl, or ether groups is described. Bromine is generated in situ from potassium bromate and hydrobromic acid. This procedure avoids the hazards associated with direct handli...

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Veröffentlicht in:Journal of chemical education 1996-03, Vol.73 (3), p.267
1. Verfasser: Schatz, Paul F
Format: Artikel
Sprache:eng
Schlagworte:
Acetanilide
Aromatic compounds
Bromination
Bromine
Bromine compounds
Chemical reactions
Experiments
Ions
Laboratories
Organic chemistry
Oxidation
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Beschreibung
Zusammenfassung:A general procedure for bromination of aromatic compounds activated with electron donating substituents such as acetamido, hydroxyl, or ether groups is described. Bromine is generated in situ from potassium bromate and hydrobromic acid. This procedure avoids the hazards associated with direct handling of bromine or bromine solutions. The results from seven aromatic ethers and anilides are reported.
ISSN:0021-9584
1938-1328
DOI:10.1021/ed073p267