Use of contraceptive depot medroxyprogesterone acetate is associated with impaired cervicovaginal mucosal integrity

BACKGROUND. Injectable depot medroxyprogesterone acetate (DMPA) is one of the most popular contraception methods in areas of high HIV seroprevalence. Evidence is accumulating that use of DMPA might be associated with an increased risk of HIV-1 acquisition by women; however, mechanisms of this associ...

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Veröffentlicht in:	The Journal of clinical investigation 2018-10, Vol.128 (10), p.4622-4638
Hauptverfasser:	Zalenskaya, Irina A, Chandra, Neelima, Yousefieh, Nazita, Fang, Xi, Adedipe, Oluwatosin E, Jackson, Suzanne S, Anderson, Sharon M, Mauck, Christine K, Schwartz, Jill L, Thurman, Andrea R, Doncel, Gustavo F
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetic acid Acquired immune deficiency syndrome AIDS Biomedical research Birth control Contraception DNA microarrays Estrogens Family planning Gene expression Genomes HIV Human immunodeficiency virus Immune response Immunosuppression Inflammation Medroxyprogesterone acetate Mucosa Serology Studies Systematic review Transcription
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