Tyrosine phosphorylation on capacitated human sperm tail detected by immunofluorescence correlates strongly with sperm–zona pellucida (ZP) binding but not with the ZP-induced acrosome reaction

BACKGROUND: Protein tyrosine phosphorylation (TP) of human sperm is related to sperm capacitation and zona pellucida (ZP) binding. The aim of this study was to determine whether the TP of capacitated sperm is a useful marker for the ability of sperm to bind to the ZP and undergo the ZP-induced acros...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Human reproduction (Oxford) 2006-04, Vol.21 (4), p.1002-1008
Hauptverfasser:	Liu, D.Y., Clarke, G.N., Baker, H.W.G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acrosome Reaction - physiology Biological and medical sciences Biomarkers Bucladesine - pharmacology Female Fluorescent Antibody Technique Gynecology. Andrology. Obstetrics Humans immunofluorescence Infertility, Male - diagnosis Male Medical sciences Phosphorylation - drug effects Sperm Capacitation - physiology Sperm Tail - metabolism Sperm Tail - physiology Sperm Tail - ultrastructure Sperm-Ovum Interactions - physiology sperm–zona binding Tetradecanoylphorbol Acetate - pharmacology Time Factors Tyrosine - metabolism tyrosine phosphorylation Zona Pellucida - physiology zona-induced acrosome reaction
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!