Synthesis, Characterization, and Anticancer Activity (MCF‐7) of Some Acetanilide‐based Heterocycles

A series of some novel 4‐(N‐substituted amino)‐acetanilide scaffolds was synthesized through the nucleophilic substitution reactions of the highly versatile N‐(4‐acetamidophenyl)‐2‐chloroacetamide (3) with various types of nucleophilic reagents such as benzothiazole‐2‐thiol, ethyl 2‐mercaptoacetate,...

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Veröffentlicht in:	Journal of heterocyclic chemistry 2018-10, Vol.55 (10), p.2334-2341
Hauptverfasser:	Abdel‐Latif, Ehab, Keshk, Eman M., Khalil, Abdel‐Galil M., Saeed, Ali, Metwally, Heba M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetanilide Ammonium Anticancer properties Cancer Chemical synthesis Malononitrile Reagents Scaffolds Substitution reactions Thiocyanates Thiophenes
Online-Zugang:	Volltext
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